Infectious Diseases

These videos cover advancements in a variety of infectious diseases, most notably SARS-CoV-2.

Hot Topics

06:06

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

Dr Matthew Gagne from Dr Daniel Douek lab speaks of his latest findings on the benefits of a vaccine boost using the original vs the Omicron strain. Read the full article https://www.cell.com/cell/fulltext/S0092-8674(22)00388-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422003889%3Fshowall%3Dtrue Review & Win! Please go to this link: shorturl.at/txLP7

05:55

High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells

In this video, Jennifer Chen from the Eisenbarth Lab in collaboration with Wilen lab at Yale University tells us their latest findings on different types of T- follicular helper cells and role in the context of infectious diseases. Read the full article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977051/ Review & Win! Please go to this link: shorturl.at/txLP7

04:09

Germinal centre-driven maturation of B cell response to mRNA vaccination

Dr Jackson Turner from Ali Ellebedy lab at Washington University School of Medicine in St. Louis describes the evolution of B-cells following vaccination against Covid-19. Read the full article https://www.nature.com/articles/s41586-022-04527-1 Review & Win! Please go to this link: shorturl.at/txLP7

06:04

Let's Prime and Boost!

Professor Akiko Iwasaki from Yale School of Medicine describes an efficient strategy called Prime and Boost to increase immune responses against Covid-19. Read the full article https://www.biorxiv.org/content/10.1101/2022.01.24.477597v1 Review & Win! Please go to this link: shorturl.at/txLP7

03:36

The Use of Boosters in Response to Latest Covid-19 Variants

Professor Akiko Iwasaki from Yale University details her latest studies on the antibody response induction against latest Sars-CoV-II variants in the context of vaccination and the use of boosters. This is the first out of 2 interviews. Read the full article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938264/ Review & Win! Please go to this link: shorturl.at/txLP7

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Coming Soon

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

Dr Matthew Gagne from Dr Daniel Douek lab speaks of his latest findings on the benefits of a vaccine boost using the original vs the Omicron strain.

Review & Win!
Please go to this link: shorturl.at/txLP7

Germinal centre-driven maturation of B cell response to mRNA vaccination

Dr Jackson Turner from Ali Ellebedy lab at Washington University School of Medicine in St. Louis describes the evolution of B-cells following vaccination against Covid-19.

Review & Win!
Please go to this link: shorturl.at/txLP7

High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells

In this video, Jennifer Chen from the Eisenbarth Lab in collaboration with Wilen lab at Yale University tells us their latest findings on different types of T- follicular helper cells and role in the context of infectious diseases.

Review & Win!
Please go to this link: shorturl.at/txLP7

Let's Prime and Boost!

Professor Akiko Iwasaki from Yale School of Medicine describes an efficient strategy called Prime and Boost to increase immune responses against Covid-19.

Read the full article
https://www.biorxiv.org/content/10.1101/2022.01.24.477597v1

Review & Win!
Please go to this link: shorturl.at/txLP7

The Use of Boosters in Response to Latest Covid-19 Variants

Professor Akkiko Iwasaki from Yale University details her latest studies on the antibody response induction against latest Sars-CoV-II variants in the context of vaccination and the use of boosters.

Read the full article
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938264/

Review & Win!
Please go to this link: shorturl.at/txLP7

Endotracheal Application of Ultraviolet A Light in Critically Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2: A First-in-Human Study

Dr Ali Rezaie from UCLA describes his latest discovery on Endotracheal Application of Ultraviolet A Light as a potential treatment against Covid-19.

Read the full article
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234768/

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Is a vaccine mandatory amongst COVID-19 infection?

Dr Nabin Shrestha from Cleveland Clinic reveals his study on the importance of vaccination in previously infected vs non-infected individuals with SARS-CoV-II.

Read the full article
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807217/

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Evolution of Sars-CoV-II

Dr. Nathaniel landau from NYU describes two of his latest findings regarding emerging mutants and their consequences.

Read the full article
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312895/

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Oral Vaccine Against Covid-19

Dr. David Klatzmann, Professor of Immunology at Sorbonne Université, describes his study on developing an oral vaccine providing mucosal immunity.
Oral Vaccine Against Covid-19
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913903/

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How Air Filtration Can Decrease Airborne Viruses

Dr. Vilas Navapurkar from Cambridge University Hospital NHS Foundation Trust describes his latest findings on the benefits of air filtration in clearing airborne pathogens including Sars-CoV-II.
Read the full article
LINK - https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab933/6414657?guestAccessKey=248e14cc-d920-4782-99b7-634e47cdaa0e&login=true

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Emotional being, sleep, and COVID-19

In his latest research, Dr. Anthony Cunningham from Harvard Medical School details people's state of mind on the days following the COVID-19 pandemic.
Read the full article
LINK - https://www.nature.com/articles/s41597-021-00886-y

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SARS-CoV-2 interactions with host genes

Dr Craig Wilen from Yale University describe a study identifying uncharacterized host genes important in SARS-CoV-2 infection.
Read the full article
LINK - https://www.cell.com/cell/fulltext/S0092-8674(20)31392-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420313921%3Fshowall%3Dtrue

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A way to study entry in biosafety level 2 lab

Dr Robert Stahelin and graduate student Caroline Plescia from Purdue University describe their latest innovative models on how to study SARS-Cov-2 entry and budding on a BSL-2 environment.
Read the full article
LINK - https://pubmed.ncbi.nlm.nih.gov/33214224/

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SARS-Cov-2 Cell Entry in a BSL2 lab

Dr Rohit Jangra, Dr M. Eugenia Dieterle and Dr Denise Haslwanter from Albert Einstein College of Medicine describe their recent findings on the generation of recombinant virus that include SARS-CoV-2 spike protein to study viral entry and immune response in a BSL-2 facility.

Read the full article
LINK - https://pubmed.ncbi.nlm.nih.gov/32738193/

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COVID-19 in Iceland

Dr Stefansson from deCODE genetics explains his latest findings related to the induced immunity in patients from Iceland following SARS-COV-2 infection.
Read the full article
LINK - https://www.nejm.org/doi/full/10.1056/NEJMoa2026116

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Immune response of vaccines in mice models

Dr Dorottya Laczkó of UPenn summarizes her studies on vaccines equivalent of the one from Pfizer and Moderna in mouse models.

Read the full article
LINK - https://www.sciencedirect.com/science/article/pii/S1074761320303265?casa_token=nPBey2d8u4wAAAAA:l__-Ilm6sOLnPs2yBp15EHbcJvJmnf58XU-4p_VuWtTdgnY2xy_Rlh7BghONZz3nkgflkHG94g

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COVID-19 and Immune Profiling

Dr. Tracy Hussell from the Lydia Becker Institute of Immunology and Inflammation describes her research on profiling the immune response upon SARS-COV-2 infection.

Read the full article
LINK - https://immunology.sciencemag.org/content/5/51/eabd6197

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